The Telethon Institute of Genetics and Medicine (TIGEM) is a multidisciplinary research institute devoted to the study of the mechanisms underlying rare genetic diseases and to the development of new therapies. The institute employs 200 Italian and foreign researchers in 20 independent research groups. Founded in 1994 by the Fondazione Telethon and located in Pozzuoli (Naples), the institute is one of the most important centers for fundamental life science research in Italy.